Eqvalan Duo Worm Dose

$17.00

This ready to use Ivermectin and Praziquantel paste dose is effective against most commmon worms. Each syringe delivers 120 mg ivermectin, sufficient to treat 600 kg of bodyweight. Each weight marking on the syringe plunger will deliver sufficient paste to treat 100 kg bodyweight.

All horses should be included in a regular parasite control program, with particular attention being paid to mares, foals and yearlings. Each syringe is sufficient to treat a horse up to 600kg. Eqvalan Duo is also safe to use for pregnant and lactating mares as well as foals from 2 months of age.

Active Ingredients: Ivermectin and Praziquantel.

Effective Against: Gastrointestinal Worms, Hairworms, Pinworms, Threadworms, Lungworm, Tapeworm, Roundworm, Bots. redworm.

Season: Spring/Autumn.

Key Benefits:

Safe for use in pregnant mares and young foals. Each syringe treats up to 600kg bodyweight.

Contains 1.55% ivermectin and 7.75% praziquantel in each syringe.

Well suited to be a major product in parasite control program.

Highly effective against gastro-intestinal, cutaneous and pulmonary nematodes and bots of horses.

 

Dosage: 1.29g per 100kg of weight.

STATEMENT OF THE ACTIVE SUBSTANCE(S)

AND OTHER INGREDIENT(S)

Each syringe contains 7.74 g of paste and delivers:

Ivermectin 15.5 mg/g

Praziquantel 77.5 mg/g

Excipients include colorants (sunset yellow FCF (El 10), titanium oxide (El 71)) and antioxidant (butylhydroxyanisole (320)).

INDICATION(S)

For the treatment of mixed cestode and nematode or arthropod infestations in horses. The following parasites of horses are sensitive to the antiparasitic effects of EQVALAN DUO, oral paste:

Adult Tapeworms: Anoplocephala perfoliata, Anoplocephala magna.

Large strongyles: Strongylus vulgaris (adults and arterial larval stages), Strongylus edentatus (adults and tissue larval stages), Strongylus equinus (adults), Triodontophorus spp (adults), Triodontophorus brevicauda, Triodontophorus serratus, Craterostomum

 

Adult and immature (intraluminal fourth-stage larvae) of small strongyles or cyathostomes, including benzimidazole-resistant strains: Coronocyclus spp., Coronocyclus coronatus, Coronocyclus labiatus, Coronocyclus labratus, Cyathostomum spp., Cyathostomum catinatum, Cyathostomum pateratum, Cylicocyclus spp., Cylicocyclus ashworthi, Cylicocyclus elongatus, Cylicocyclus insigne, Cylicocyclus leptostomum, Cylicocyclus nassatus, Cylicodontophorus spp., Cy/icodontophorus bicornatus, Cylicostephanus spp., Cylicostephanus calicatus, Cylicostephanus goldi, Cylicostephanus longibursatus, Cylicostephanus minutus, Parapoteriostomum spp., Parapoteriostomum mettami,

Petrovinema spp., Petrovinema poculatum,

Poteriostomum spp.

Adult hairworms: Trichostrongylus axel

Adult and immature (fourth-stage larvae) pinworms: Oxyuris equi

Adult, third-and fourth-stage larvae of roundworms (ascarids): Parascaris equorum.

Microfilariae of neck threadworms: Onchocerca spp.

Adult intestinal threadworms: Strongyloides westeri. Adult large-mouth stomach worms: Habronema muscae-

Oral and gastric stages of bots: Gasterophilus spp. Adult and immature (inhibited fourth-stage larvae) lungworms: Dictyocaulus arnfie/di.

CONTRAINDICATIONS

Do not use in mares producing milk for human consumption.

The product has been formulated for use in horses only. Cats, dogs, especially Collies, Old English Sheepdogs and related breeds or crosses, and also turtles and tortoises may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.

ADVERSE REACTIONS

Some horses with heavy infections of Onchocerca spp. microfilariae have experienced oedema and pruritus following treatment; such reactions were assumed to be the result of the death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.

In cases of heavy infestations with tapeworms, signs of mild, transient colic and loose stool may be observed.

Following administration of EQVALAN DUO, there have been rare reports of inflammation of the mouth, lip and tongue which results in various clinical signs such as oedema, hypersalivation, erythema, tongue disorder and stomatitis. These reactions have been transitory in nature, appearing within 1 hour and abating within 24 to 48 hours following administration. In case of severe oral reactions symptomatic treatment is recommended

If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.

TARGET SPECIES

Horses

DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD

OF ADMINISTRATION

Oral _use

 

The recommended dosage is 200 mcg ivermectin per kilogram of bodyweight and 1 mg praziquantel per kilogram of body weight corresponding to 1.29 g of paste per 100 kg body weight in a single administration.

Bodyweight and dosage should be accurately determined prior to treatment. The contents of one syringe will treat horses up to 600 kg. Calibrated markings are provided at 100 kg bodyweight intervals. The syringe should be adjusted to the calculated dosage by setting the ring on the appropriate place on the plunger.

Parasite control programme

Veterinary advice should be given on appropriate dosing programmes and stock management to achieve adequate parasite control for both tapeworm and roundworm infestations.

 

ADVICE ON CORRECT ADMINISTRATION

EQVALAN DUO, oral paste is for oral administration only. While holding the plunger, turn the knurled ring on the plunger 1/4 turn to the left and slide it so the stop ring is at the prescribed weight marking. Lock the ring in place by turning it 1/4 turn to the right in order to bring the two arrows, the one visible on the ring and the one on the plunger rod, into alignment. Make sure the horse's mouth contains no feed. Remove the cover from the tip of the syringe. Insert the syringe tip into the horse's mouth at the interdental space and deposit the paste on the base of the tongue. Immediately raise the horse's head for a few seconds after dosing and ensure that the paste is consumed.

WITHDRAWALFERIOD Meat: 30 days.

SPECIAL STORAGE PRECAUTIONS Store in the original container.

Replace cap after use.

Do not use after the expiry date stated on the label. Shelf life after first opening the immediate packaging:

2 years.

Keep out of the reach and sight of children.

SPECIAL WARNING(S)

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: - Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.

- Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device.

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used

Resistance to macrocyclic lactones (which includes ivermectin) has been reported in Parascaris equorum in horses in the EU. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of gastro-intestinal nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

Special precautions for use in animals

Safety studies were not conducted in foals younger than 2 months of age or in stallions, therefore the use of EQVALAN DUO, oral paste is not recommended in these categories of animals.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Wash hands after use.

IE. 10454/036/001

Licensed merchant

Do not smoke, drink or eat while handling the product This product may eye irritation.•therefore, the user should avoid contact of the product with the skin and the

Use during pregnancy, lactation or lay

Studies performed in laboratory animals showed no teratogenic or embryotoxic effect of either ivermectin or praziquantel at the recommended doses during therapy. Ivermectin-praziquantel combination can be used after the first three months of gestation and during lactation. In the absence of clinical data in early pregnancy EQVALAN DUO can only be used in the first three months of gestation according to a risk benefit analysis by the veterinarian.

Overdose (symptoms, emergency procedures, antidotes), if necessary

No undesirable effects related to treatment were observed in 2 month old horses treated with EQVALAN DUO, oral paste at up to three times the recommended dose and in adult horses treated at ten times the recommended dose. Transient decreased food consumption, increased body temperature, salivation and impairment of vision were noticed in horses treated twice with an ivermectin oral paste or once with EQVALAN DUO, oral paste at ten times the recommended dose (i.e., 2 mg/kg b.w.). All changes disappeared within five days.

No antidote has been identified; however, symptomatic therapy may be beneficial.

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF

UNUSED PRODUCT OR WASTE MATERIALS, IF ANY EXTREMELY DANGEROUS FOR FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used syringes. Dispose of any unused product and empty syringes in accordance with guidance from your local waste regulation authority.

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